{"id":67579,"date":"2021-06-22T15:47:09","date_gmt":"2021-06-22T19:47:09","guid":{"rendered":"https:\/\/www.agribusinessglobal.com\/?p=67579"},"modified":"2021-07-12T10:31:59","modified_gmt":"2021-07-12T14:31:59","slug":"syngenta-partners-with-enko-to-accelerate-molecule-discovery","status":"publish","type":"post","link":"https:\/\/www.agribusinessglobal.com\/es\/agrochemicals\/syngenta-partners-with-enko-to-accelerate-molecule-discovery\/","title":{"rendered":"Syngenta se asocia con Enko para acelerar el descubrimiento de mol\u00e9culas"},"content":{"rendered":"
\"Enko

Los investigadores de Enko eval\u00faan un nuevo control de plagas en el ma\u00edz. Cr\u00e9dito de la foto Tim Llewellyn<\/p><\/div>\n

Por segunda vez este a\u00f1o, Syngenta se ha asociado con una empresa de investigaci\u00f3n que aprovecha las nuevas t\u00e9cnicas de descubrimiento de mol\u00e9culas utilizadas en el desarrollo farmac\u00e9utico para llevar nuevas IA al mercado agr\u00edcola.<\/p>\n

Empresa de salud de cultivos Enko<\/a> y Syngenta anunciaron hoy una asociaci\u00f3n de varios a\u00f1os para atacar plagas espec\u00edficas y dise\u00f1ar nuevas mol\u00e9culas para controlarlas. Las empresas a\u00fan est\u00e1n identificando proyectos prioritarios en conjunto, y los nuevos herbicidas para combatir las malezas resistentes en el ma\u00edz y la soja en las Am\u00e9ricas podr\u00edan ser probablemente los primeros objetivos.<\/p>\n

As\u00ed es como funciona:<\/p>\n

\"Aerial<\/a>

Vista a\u00e9rea de la sede de Enko en Mystic, CT.<\/p><\/div>\n

El enfoque basado en objetivos de Enko combina tecnolog\u00edas novedosas de descubrimiento de f\u00e1rmacos como bibliotecas codificadas por ADN con aprendizaje autom\u00e1tico y biolog\u00eda estructural para mejorar dr\u00e1sticamente la escala y la velocidad de la I + D en protecci\u00f3n de cultivos. El enfoque permite a los cient\u00edficos analizar m\u00e1s de 120 mil millones de compuestos simult\u00e1neamente para identificar mol\u00e9culas que se unen como un candado y una llave a variantes enzim\u00e1ticas espec\u00edficas en las plagas. Estas mol\u00e9culas altamente selectivas son m\u00e1s efectivas en cantidades menores y no impactan variantes enzim\u00e1ticas similares en otros organismos, lo que establece barreras de seguridad desde el primer paso del descubrimiento.<\/p>\n

El aprendizaje autom\u00e1tico permite a Enko emparejar compuestos que podr\u00edan ser efectivos para controlar una plaga objetivo utilizando nuevas v\u00edas y al mismo tiempo detectar ese compuesto en busca de toxicidad ambiental y no objetivo. Luego puede dise\u00f1ar una v\u00eda de origen y una formulaci\u00f3n. El proceso podr\u00eda reducir a la mitad el cronograma de I + D, seg\u00fan Enko.<\/p>\n

"Tenemos 120 mil millones de compuestos en nuestra biblioteca, se necesitar\u00edan muchas vidas para evaluarlos usando m\u00e9todos tradicionales", dijo la directora ejecutiva de Enko, Jacqueline Heard. AgriBusiness Global<\/em>. Estamos encontrando los puntos de partida y tomando el modelado y la IA desde all\u00ed para dise\u00f1ar compuestos como un candado y una llave para aprovechar el modelado y el dise\u00f1o basado en estructuras para descubrir nueva materia qu\u00edmica ".<\/p>\n

Syngenta firm\u00f3 un acuerdo similar con Insilico Medicine<\/a> en febrero, ilustrando el enfoque y la inversi\u00f3n de Syngenta en productos de protecci\u00f3n de cultivos de pr\u00f3xima generaci\u00f3n utilizando el aprendizaje autom\u00e1tico para descubrir nuevas v\u00edas para el control de plagas.<\/p>\n

\"Jacqueline

Jacqueline Heard, directora ejecutiva de Enko<\/p><\/div>\n

Se espera que los acuerdos generen m\u00e1s productos nuevos de los que se est\u00e1n introduciendo actualmente sobre una base anual, y se comercializar\u00e1n m\u00e1s r\u00e1pidamente, dice Heard.<\/p>\n

"En nuestro propio proceso de descubrimiento, comenzamos con algunos objetivos y qu\u00edmicas de herbicidas novedosos, por lo que en 2-5 a\u00f1os, definitivamente tendremos mol\u00e9culas en comercializaci\u00f3n y tendremos una estrategia de comercializaci\u00f3n m\u00e1s frecuente en el futuro", dijo. .<\/p>\n

La capacidad de atacar plagas espec\u00edficas y dise\u00f1ar nuevas mol\u00e9culas para controlarlas de una manera m\u00e1s eficiente podr\u00eda reducir el costo de desarrollo, lo que podr\u00eda hacer que los productos para las econom\u00edas en desarrollo sean m\u00e1s asequibles tanto para los fabricantes como para las granjas. En su comunicado de prensa, Enko dice que la perspectiva de opciones accesibles y soluciones m\u00e1s eficientes para el tratamiento de plagas y enfermedades nuevas beneficiar\u00e1 dram\u00e1ticamente a los agricultores de todo el mundo. En particular, Enko est\u00e1 comprometido con el desarrollo de productos fitosanitarios asequibles para los peque\u00f1os agricultores de \u00c1frica, Am\u00e9rica del Sur y Asia, que se enfrentan a una desventaja desproporcionada de las plagas debido al cambio clim\u00e1tico y est\u00e1n desatendidos por los productos del mercado actual.<\/p>\n

Syngenta, con sus redes de distribuci\u00f3n en todo el mundo, liderar\u00e1 la comercializaci\u00f3n de los productos co-desarrollados por Enko.<\/p>","protected":false},"excerpt":{"rendered":"

Las empresas desarrollar\u00e1n conjuntamente productos qu\u00edmicos novedosos que utilicen IA para apuntar a presiones de plagas espec\u00edficas.<\/p>","protected":false},"author":14,"featured_media":67580,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4,1849],"tags":[54],"class_list":["post-67579","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-agrochemicals","category-sourcing-insider","tag-featured-home"],"yoast_head":"\nSyngenta Partners with Enko to Accelerate Molecule Discovery - AgriBusiness Global<\/title>\n<meta name=\"description\" content=\"Companies to co-develop novel chemistries using AI to target specific pest pressures.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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