{"id":135756,"date":"2026-11-10T11:27:28","date_gmt":"2026-11-10T16:27:28","guid":{"rendered":"https:\/\/www.agribusinessglobal.com\/?p=135756"},"modified":"2026-11-10T11:27:28","modified_gmt":"2026-11-10T16:27:28","slug":"biotalys-achieves-critical-manufacturing-milestone-for-first-commercial-biofungicide-evoca-ng","status":"publish","type":"post","link":"https:\/\/www.agribusinessglobal.com\/pt\/biopesticides\/biotalys-achieves-critical-manufacturing-milestone-for-first-commercial-biofungicide-evoca-ng\/","title":{"rendered":"A Biotalys alcan\u00e7a um marco cr\u00edtico na fabrica\u00e7\u00e3o de seu primeiro biofungicida comercial, o EVOCA NG."},"content":{"rendered":"<p><a href=\"https:\/\/www.biotalys.com\/media\/news\/biotalys-achieves-critical-manufacturing-milestone-first-commercial-biofungicide-evocar\" target=\"_blank\" rel=\"noopener\">Biotalys<\/a>, an Agricultural Technology (AgTech) company developing protein-based biocontrol solutions for sustainable crop protection, has announced the successful completion of a pilot production campaign for EVOCA NG, the company\u2019s first AGROBODY\u00ae commercial product candidate.<\/p>\n<p>Conducted in partnership with <a href=\"https:\/\/21st.bio\/\" target=\"_blank\" rel=\"noopener\">21\u00ba.BIO<\/a>, a leading precision fermentation technology provider, the campaign successfully demonstrated the consistency and scalability of Biotalys\u2019 manufacturing process for EVOCA NG across five consecutive production batches. This important manufacturing achievement provides critical material and process validation data to support product registrations activities, while further advancing the company\u2019s readiness for future commercial-scale production and market launch.<\/p>\n<p>\u201cThis is a key milestone in the transition of EVOCA NG from development to commercialization,\u201d said Carlo Boutton, Chief Executive Officer of Biotalys. \u201cFive consecutive production batches demonstrate the robustness and reproducibility of our manufacturing approach. Through our collaboration with 21st.BIO, we have also achieved a more than 15-fold improvement in production efficiency compared with EVOCA. We are now ready to move into the next phase towards commercialization: scaling up production with contract manufacturing organizations.\u201d<\/p>\n<p>EVOCA NG is developed on Biotalys\u2019 proprietary AGROBODY technology platform to help fruit and vegetable growers effectively control the key fungal diseases Botrytis (grey mold) and powdery mildew. Expected to be Biotalys\u2019 first commercial biofungicide, EVOCA NG is planned for registration in both the U.S. and E.U. in 2029, targeting a combined market of approximately USD 1.1 billion.<\/p>\n<p>EVOCA NG has the same bioactive ingredient as EVOCA, the first-generation product that received EPA approval in the U.S. in December 2025 and state approval in Florida and California in 2026. Regulatory review of EVOCA in the E.U. is ongoing, with the European Food Safety Authority (EFSA) expected to finalize its review by the end of this year or early next year following the recent submission of additional data. The regulatory progress of EVOCA paves the way for EVOCA NG, for which Biotalys expects a significantly shorter regulatory trajectory in both the U.S. and E.U. through equivalency or amendment procedures.<\/p>","protected":false},"excerpt":{"rendered":"<p>Pilot production campaign delivers more than 15-fold improvement in production efficiency, paving the way for scale-up.<\/p>","protected":false},"author":110,"featured_media":71850,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[22,489],"tags":[],"class_list":["post-135756","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biopesticides","category-industry-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biotalys Achieves Critical Manufacturing Milestone for First Commercial Biofungicide EVOCA NG - AgriBusiness Global<\/title>\n<meta name=\"description\" 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