{"id":75090,"date":"2024-01-25T10:46:11","date_gmt":"2024-01-25T15:46:11","guid":{"rendered":"https:\/\/www.agribusinessglobal.com\/?p=75090"},"modified":"2024-01-25T10:46:11","modified_gmt":"2024-01-25T15:46:11","slug":"moa-reveals-data-on-next-generation-herbicides-with-new-modes-of-action-and-progress-towards-field-trials","status":"publish","type":"post","link":"https:\/\/www.agribusinessglobal.com\/pt\/agrochemicals\/herbicides\/moa-reveals-data-on-next-generation-herbicides-with-new-modes-of-action-and-progress-towards-field-trials\/","title":{"rendered":"Moa revela dados sobre herbicidas de \u00faltima gera\u00e7\u00e3o com novos modos de a\u00e7\u00e3o e progresso em dire\u00e7\u00e3o a ensaios de campo"},"content":{"rendered":"

Tecnologia Moa<\/a>, a empresa de biotecnologia agr\u00edcola que combate ervas daninhas resistentes a herbicidas que amea\u00e7am a seguran\u00e7a alimentar mundial, revelou dados que demonstram o poder de sua plataforma de descoberta de herbicidas de \u00faltima gera\u00e7\u00e3o Galaxy e anunciou que iniciar\u00e1 testes de campo internacionais em 2024. Os testes planejados nos hemisf\u00e9rios norte e sul cobrir\u00e3o diversas mol\u00e9culas l\u00edderes derivadas de novos modos de a\u00e7\u00e3o (MOAs) de herbicidas.<\/p>\n

Os dados inovadores foram apresentados pelo Diretor Cient\u00edfico da Moa, Dr. Xavier Jacq, na 64\u00aa Confer\u00eancia Anual da Weed Science Society of America (WSSA), realizada em San Antonio, Texas, em 24 de janeiro, em um simp\u00f3sio sobre Novas Abordagens para Descoberta de Herbicidas e Bioherbicidas. Em sua apresenta\u00e7\u00e3o intitulada Galaxy, uma plataforma de imagens de alto conte\u00fado que permite a descoberta de novos herbicidas<\/em>O Dr. Jacq forneceu uma vis\u00e3o geral do inovador e sistem\u00e1tico mecanismo de descoberta de herbicidas em larga escala da Moa, que est\u00e1 encontrando novas classes de MOAs com atividade herbicida \u00fanica e potencialmente poderosa uma ordem de magnitude mais r\u00e1pido do que os m\u00e9todos tradicionais.<\/p>\n

Ervas daninhas resistentes a herbicidas amea\u00e7am a seguran\u00e7a alimentar e a produtividade agr\u00edcola, e s\u00e3o um grande problema para um n\u00famero crescente de agricultores em todo o mundo. Sem herbicidas eficazes, os agricultores podem perder at\u00e9 40% de sua produ\u00e7\u00e3o agr\u00edcola como resultado do crescimento de ervas daninhas, conforme destacado em um relat\u00f3rio recente da Reuters: Ervas daninhas que destroem planta\u00e7\u00f5es avan\u00e7am em terras agr\u00edcolas dos EUA \u00e0 medida que produtos qu\u00edmicos perdem efic\u00e1cia<\/a>.<\/p>\n

\u201cA necessidade de inova\u00e7\u00e3o para desenvolver herbicidas de pr\u00f3xima gera\u00e7\u00e3o para superar a resist\u00eancia das ervas daninhas aos herbicidas atuais est\u00e1 se tornando cada vez mais aparente\u201d, diz o Dr. Xavier Jacq, Diretor Cient\u00edfico da Moa Technology. \u201cPor d\u00e9cadas, a inova\u00e7\u00e3o em herbicidas tem se apoiado em an\u00e1logos dentro de fam\u00edlias qu\u00edmicas que trabalham com modos de a\u00e7\u00e3o estabelecidos, ent\u00e3o o problema real \u00e9 como encontrar uma nova gera\u00e7\u00e3o de herbicidas trabalhando de novas maneiras para enfrentar a seca na nova descoberta da MOA \u2013 um desafio que acreditamos estar a caminho de resolver na Moa.\u201d<\/p>\n

O Dr. Jacq foi recrutado pela Moa com experi\u00eancia em biotecnologia de empresas como KuDOS Pharmaceuticals, Mission Therapeutics, Almac Discovery e Dunad Therapeutics; ele lidera uma equipe de cientistas que aplica tecnologias que t\u00eam sido usadas efetivamente na descoberta de medicamentos nas \u00faltimas d\u00e9cadas \u00e0 descoberta de herbicidas.<\/p>\n

As plataformas de biotecnologia de ponta propriet\u00e1rias da Moa usam a plataforma Galaxy fenot\u00edpica liderada por plantas para rastrear uma enorme diversidade de produtos qu\u00edmicos naturais e sint\u00e9ticos em plantas inteiras miniaturizadas para identificar rapidamente uma abund\u00e2ncia de novos MOAs herbicidas nunca comercializados em escala, velocidade e custo sem precedentes, respondendo \u00e0s perguntas "\u00c9 um herbicida e funciona de uma nova maneira?" O Target, o pr\u00f3ximo passo em seu processo, combina uma constela\u00e7\u00e3o de gen\u00e9tica poderosa, fenot\u00edpica, bioqu\u00edmica, OMICs e bioinform\u00e1tica para identificar rapidamente a prote\u00edna alvo, a via e o novo MOA, acelerando as previs\u00f5es de seguran\u00e7a e otimiza\u00e7\u00e3o em herbicidas prontos para a fazenda.<\/p>\n

Este conjunto de plataformas j\u00e1 examinou mais de 750.000 compostos qu\u00edmicos sint\u00e9ticos e naturais derivados de produtos. Em apenas dois anos, a Moa identificou mais de 60 novas \u00e1reas MOA e caracterizou seu desempenho contra pain\u00e9is de ervas daninhas e culturas em suas instala\u00e7\u00f5es de estufa.<\/p>\n

Dr. Jacq diz: \u201cHouve apenas um herbicida com um novo MOA introduzido no mercado nos \u00faltimos 35 anos, e nenhum para muitas das grandes culturas de que o mundo depende. Na Moa, estamos avan\u00e7ando um pipeline crescente de novos herbicidas, incluindo bioherbicidas, para testes de campo em ritmo acelerado. A velocidade e o poder da nossa abordagem significam que entraremos em testes de campo internacionais nos hemisf\u00e9rios norte e sul em 2024 com m\u00faltiplas mol\u00e9culas l\u00edderes derivadas de novos MOAs.\u201d<\/p>\n

Apoiada por capital de risco, altamente ambiciosa e de r\u00e1pido crescimento, a Moa Technology, que foi desmembrada da Universidade de Oxford, criou uma grande e dedicada equipe de P&D com o objetivo de mudar o paradigma na descoberta de herbicidas, para dar suporte aos agricultores com melhores herbicidas que melhorem a sa\u00fade e a produtividade das culturas e mitiguem o impacto das mudan\u00e7as clim\u00e1ticas.<\/p>","protected":false},"excerpt":{"rendered":"

Os testes planejados nos hemisf\u00e9rios norte e sul abranger\u00e3o diversas mol\u00e9culas principais derivadas de novos MOAs de herbicidas.<\/p>","protected":false},"author":110,"featured_media":73985,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19,489],"tags":[],"class_list":["post-75090","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-herbicides","category-industry-news"],"yoast_head":"\nMoa Reveals Data on Next-Generation Herbicides with New Modes of Action and Progress Towards Field Trials - AgriBusiness Global<\/title>\n<meta name=\"description\" content=\"The trials planned in the northern and southern hemispheres will cover multiple lead molecules derived from new herbicide MOAs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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