{"id":80871,"date":"2025-12-10T12:56:26","date_gmt":"2025-12-10T17:56:26","guid":{"rendered":"https:\/\/www.agribusinessglobal.com\/?p=80871"},"modified":"2025-12-02T16:01:29","modified_gmt":"2025-12-02T21:01:29","slug":"the-evolving-role-of-generics-lessons-from-chlorpyrifos","status":"publish","type":"post","link":"https:\/\/www.agribusinessglobal.com\/pt\/agrochemicals\/insecticides\/the-evolving-role-of-generics-lessons-from-chlorpyrifos\/","title":{"rendered":"O papel em evolu\u00e7\u00e3o dos gen\u00e9ricos: li\u00e7\u00f5es do clorpirif\u00f3s"},"content":{"rendered":"

O clorpirif\u00f3s passou por mudan\u00e7as dr\u00e1sticas em sua trajet\u00f3ria de mercado, de uma mol\u00e9cula propriet\u00e1ria de grande sucesso a um ingrediente ativo gen\u00e9rico comercializado globalmente.<\/p>\n

Agroneg\u00f3cio Global<\/strong> Conversei com Ram Seethapathi, Presidente e CEO da America of Produtos Qu\u00edmicos Gharda,<\/a> Uma das empresas pioneiras na produ\u00e7\u00e3o de gen\u00e9ricos de clorpirif\u00f3s, tanto em produtos t\u00e9cnicos quanto formulados, para aprender sobre a trajet\u00f3ria desse gen\u00e9rico no mercado.<\/p>\n

ABG: De que forma a expira\u00e7\u00e3o da patente do clorpirif\u00f3s alterou o cen\u00e1rio competitivo dos agroqu\u00edmicos, particularmente em termos de pre\u00e7os e acesso ao mercado para produtores regionais em compara\u00e7\u00e3o com as multinacionais?<\/strong><\/p>\n

Ram Seethapathi:<\/strong> O clorpirif\u00f3s \u00e9 um composto muito antigo \u2014 sua patente expirou h\u00e1 mais de quatro d\u00e9cadas. A Gharda foi uma das primeiras empresas a fabricar produtos t\u00e9cnicos e de uso final de clorpirif\u00f3s de forma gen\u00e9rica, utilizando um processo alternativo inovador desenvolvido pelo Dr. Gharda. Ao contr\u00e1rio da rota original da Dow Elanco, que utilizava piridina, nosso processo emprega \u00e1cido ac\u00e9tico como mat\u00e9ria-prima inicial. Essa abordagem tornou a fabrica\u00e7\u00e3o mais segura e sustent\u00e1vel, evitando os riscos associados ao manuseio da piridina.<\/p>\n

Como acontece com qualquer produto gen\u00e9rico, inicialmente foi dif\u00edcil competir com as marcas j\u00e1 consolidadas das grandes multinacionais. Com o tempo, por\u00e9m, nossos esfor\u00e7os de desenvolvimento de mercado e a produ\u00e7\u00e3o com boa rela\u00e7\u00e3o custo-benef\u00edcio nos permitiram oferecer produtos com pre\u00e7os competitivos para distribuidores em todo o mundo, beneficiando, em \u00faltima an\u00e1lise, os produtores com custos mais baixos por hectare.<\/p>\n

A concorr\u00eancia sempre foi ben\u00e9fica para os consumidores. O pre\u00e7o do clorpirif\u00f3s t\u00e9cnico, que antes girava em torno de $25 por quilograma, caiu gradualmente para menos de $10 por quilograma \u00e0 medida que o produto amadureceu. O produto de alta qualidade da Gharda foi consistentemente aceito em mercados desenvolvidos como os EUA, enquanto a ado\u00e7\u00e3o foi ainda mais r\u00e1pida em outras regi\u00f5es do mundo.<\/p>\n

ABG: Quais estrat\u00e9gias permitiram que as empresas de gen\u00e9ricos prosperassem onde as grandes multinacionais enfrentaram desafios?<\/strong><\/p>\n

RS:<\/strong> Operacionalmente, as empresas de servi\u00e7os gen\u00e9ricos tendem a ser mais \u00e1geis do que as grandes corpora\u00e7\u00f5es. Custos operacionais mais baixos, tomada de decis\u00f5es mais r\u00e1pida e a capacidade de se adaptar rapidamente \u00e0s mudan\u00e7as na din\u00e2mica do mercado s\u00e3o essenciais para nossa resili\u00eancia e crescimento cont\u00ednuo.<\/p>\n

ABG: Que li\u00e7\u00f5es a hist\u00f3ria do clorpirif\u00f3s oferece sobre o papel dos gen\u00e9ricos na forma\u00e7\u00e3o dos mercados globais de prote\u00e7\u00e3o de cultivos?<\/strong><\/p>\n

RS:<\/strong> O clorpirif\u00f3s est\u00e1 entre as mol\u00e9culas mais estudadas na prote\u00e7\u00e3o de cultivos. Embora as controv\u00e9rsias em torno de sua seguran\u00e7a persistam, a gera\u00e7\u00e3o cont\u00ednua de dados e a revis\u00e3o regulat\u00f3ria t\u00eam apoiado seu uso cont\u00ednuo em muitos sistemas agr\u00edcolas.<\/p>\n

Com a redu\u00e7\u00e3o dos projetos de pesquisa e desenvolvimento e a crescente complexidade e custo das aprova\u00e7\u00f5es de novas mol\u00e9culas, defender os produtos existentes com base em evid\u00eancias cient\u00edficas s\u00f3lidas \u00e9 fundamental. Educar o p\u00fablico sobre os dados de seguran\u00e7a e os fundamentos cient\u00edficos das decis\u00f5es regulat\u00f3rias pode ajudar a evitar rea\u00e7\u00f5es emocionais ou sem embasamento cient\u00edfico em quest\u00f5es de prote\u00e7\u00e3o de cultivos.<\/p>\n

Os medicamentos gen\u00e9ricos desempenham um papel crucial para garantir a acessibilidade e a disponibilidade. Atualmente, os gen\u00e9ricos representam cerca de 751 mil e trinta trilh\u00f5es de libras do mercado global de prote\u00e7\u00e3o de cultivos \u2014 e essa participa\u00e7\u00e3o continuar\u00e1 a crescer \u00e0 medida que mais patentes expirarem. Em muitas economias em desenvolvimento, onde o acesso e a acessibilidade continuam sendo vitais, manter a confian\u00e7a em gen\u00e9ricos bem estudados, como o clorpirif\u00f3s, por meio da gera\u00e7\u00e3o cont\u00ednua de dados e da comunica\u00e7\u00e3o transparente, \u00e9 essencial.<\/p>\n

ABG: Olhando para o futuro, como voc\u00ea v\u00ea a evolu\u00e7\u00e3o do papel das empresas de gen\u00e9ricos na agricultura global?<\/strong><\/p>\n

RS:<\/strong> A experi\u00eancia com o clorpirif\u00f3s destaca a import\u00e2ncia da inova\u00e7\u00e3o cont\u00ednua na \u00e1rea de gen\u00e9ricos \u2014 por meio de melhorias de processos, gest\u00e3o de dados e efici\u00eancia. Os fabricantes de gen\u00e9ricos devem manter o compromisso com a qualidade, a seguran\u00e7a e a sustentabilidade, garantindo ao mesmo tempo que os produtores continuem a ter acesso a solu\u00e7\u00f5es economicamente vi\u00e1veis. \u00c0 medida que as press\u00f5es regulat\u00f3rias e os custos dos insumos aumentam, esse equil\u00edbrio definir\u00e1 a pr\u00f3xima fase do setor.<\/p>","protected":false},"excerpt":{"rendered":"

Ram Seethapathi, CEO da Gharda, descreve como os gen\u00e9ricos remodelaram o clorpirif\u00f3s \u2014 desde o poder de precifica\u00e7\u00e3o at\u00e9 o acesso global \u2014 e o que isso significa para a prote\u00e7\u00e3o futura das culturas.<\/p>","protected":false},"author":1477,"featured_media":70863,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1917,4,20],"tags":[54],"class_list":["post-80871","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-abg-update-feature","category-agrochemicals","category-insecticides","tag-featured-home"],"yoast_head":"\nThe Evolving Role of Generics: Lessons from Chlorpyrifos - AgriBusiness Global<\/title>\n<meta name=\"description\" content=\"Gharda CEO Ram Seethapathi outlines how generics reshaped chlorpyrifos \u2014 from pricing power to global access \u2014 and what it means for future crop 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