Bayer CropScience AG and Precision BioSciences Inc. have successfully inserted a gene into a specific desired location in cotton using Precision’s Directed Nuclease Editor (DNE) technology, according to a press release.
拜耳作物科学公司的科学家使用一种被称为 DNE 工程大范围核酸酶的酶，该酶由 Precision 生产，旨在将转基因插入植物品系中现有转基因附近。据两家公司称，这种方法可以减少生产新植物特性所需的时间，并消除与当前产品开发方法相关的复杂性。这是已知的第一份使用工程核酸酶在棉花中进行位点特异性插入的报告。
Precision’s DNE technology, which is based on the production of DNA-cleaving enzymes called engineered meganucleases, enables crop researchers at Bayer to delete, insert, or otherwise modify genes at user-defined sites within plant genomes. By facilitating the direct introduction of value adding traits into plant species, the technology can streamline product development and reduce the time it takes to get a product ready for the market, according to the release.
“This technology milestone is a world first and delivers enormous capacity for Bayer to precisely target and more efficiently deliver significant benefits in key crops to farmers globally. And this is just the beginning,” said Dr Johan Botterman, head of bioScience product research at Bayer CropScience.
Precision BioSciences and Bayer CropScience are developing additional DNE-engineered meganucleases for use across the company’s crop platforms.