完整的马铃薯枯萎病病原体基因组测序

据报道,美国农业部农业研究服务中心 (ARS) 的科学家已经对导致臭名昭著的爱尔兰马铃薯饥荒和最近美国东部马铃薯和番茄作物损失的病原体的完整基因组进行了测序。 ARS新闻服务.

The fungus, Phytophthora infestans, causes the disease commonly known as late blight, the most destructive potato disease. It can also infect tomatoes and other members of the Solanaceae family. Once the pathogen attacks, there is little that can be don e to save the crop, which can be completely destroyed in just one week, according to ARS. Additionally, the pathogen’s ability to quickly mutate and develop resistance to current fungicides makes it difficult to control.

ARS plant pathologist Richard Jones, with the agency’s Genetic Improvement of Fruits and Vegetables Laboratory in Beltsville, Maryland, US, led a group responsible for examining and annotating the genes that produce enzymes to degrade a plant’s cell wall. Jones and colleagues found located close to each other on the genome of P. infestans several groups of enzymes which attack the surface of the plant, allowing the pathogen to break through and
begin feeding on the plant’s nutrients. The scientists believe two of these enzyme groups may be used by the pathogen at the initial stage of infection.

The researchers were also the first to identify and report a unique pattern of gene segments called introns in the pathogen’s genome that give the pathogen the ability to produce different proteins from the same gene and attack different compounds within the plant cell wall. This may further explain how the late blight pathogen is so successful in attacking plants, according to Jones.

这项研究发表在科学杂志上 自然.